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Synthesis and Characterization of Novel Schiff base Cu(II) Complexes: Antimicrobial and Molecular docking Studies

AP Arumugam , G Elango and S Guhanathan

KEYWORDS

EPR, 3,4-diaminobenzophenone, Antimicrobial Activity, Molecular Docking.

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ABSTRACT

N2O2 type complexes of C+2uion have been synthesized by the reaction of Salicylaldehyde / 3,4-diaminobenzophenone / acetyl acetoneand glutaric anhydride. The ligands and respective metal complexes was established through spectroscopic data (FT-IR, UV-Vis,1H NMR and 13C NMR). They are non-electrolytic in nature as their molar conductivities (ΛM) in DMSO of 10-3 M solution from the EPR study the complexes proposed to be octahedral geometry. All the metal complexes have been screened for their antibacterial activity andthe predicted binding affinity using molecular docking studies.

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URL http://www.jce.chitkara.edu.in/pdf/papers/vol-3-no-2/JCE001_Arumugam.pdf
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