Synthesis and Characterization of Novel Schiff base Cu(II) Complexes: Antimicrobial and Molecular docking Studies

AP Arumugam; G Elango; S Guhanathan

doi:10.15415/jce.2017.32006

Authors

AP Arumugam Department of Chemistry, Govt. Arts College, Tiruvannamalai, Tamil Nadu., India.
G Elango Department of Chemistry, Govt. Arts College, Tiruvannamalai, Tamil Nadu., India
S Guhanathan Department of Chemistry, Muthurangam Government Arts College (Autonomous), Vellore, Tamilnadu., India.

DOI:

https://doi.org/10.15415/jce.2017.32006

Keywords:

EPR, 3,4-diaminobenzophenone, Antimicrobial Activity, Molecular Docking

Abstract

N₂O₂ type complexes of C⁺²uion have been synthesized by the reaction of Salicylaldehyde/ 3,4-diaminobenzophenone/ acetyl acetoneand glutaric anhydride. The ligands and respective metal complexes was established through spectroscopic data (FT-IR, UV-Vis,1H NMR and ¹³C NMR). They are non-electrolytic in nature as their molar conductivities (ΛM) in DMSO of 10^-3 M solution from the EPR study the complexes proposed to be octahedral geometry. All the metal complexes have been screened for their antibacterial activity andthe predicted binding affinity using molecular docking studies.

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