One-Pot Synthesis of Schiff Base Compounds Derived From 2-Nitro Benzoic Acid With Aldehydes

Authors

  • A.V.G.S. Prasad Department of Chemistry, Nizam College, Hyderabad, A.P, India
  • P. Venkateswara Rao Department of Chemistry, Nizam College, Hyderabad, A.P, India

DOI:

https://doi.org/10.15415/jce.2014.11001

Keywords:

Schiff bases, 2-nitro benzoic acid, ntibacterial activity and Antifungal activity

Abstract

In the present study, an intermolecular reductive Schiff base formation from nitroarenes and benzaldehydes to yield diarylimines is carried out in the presence of iron powder and dilute acid This type of excellent method avoids the use of hazardous solvents, longer reaction time and tedious work up procedure. Advantage of this efficient method is excellent yield of products in crystalline form, short reaction time, simplicity of work up procedure and no use of any type of hazardous solvents. Simply this reaction is an economically attractive method for synthesis of Schiff base compounds. All these Schiff base compounds were characterized by means of IR, 1H-NMR analysis data. The Schiff base ligands have also been tested in vitro for their antibacterial and antifungal activity. The experimental results suggest that Schiff base ligands are more potent in antibacterial and antifungal activities.

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Published

2014-09-03

How to Cite

A.V.G.S. Prasad, & P. Venkateswara Rao. (2014). One-Pot Synthesis of Schiff Base Compounds Derived From 2-Nitro Benzoic Acid With Aldehydes. Journal of Chemistry, Environmental Sciences and Its Applications, 1(1), 7–14. https://doi.org/10.15415/jce.2014.11001

Issue

Vol. 1 No. 1 (2014)

Section

Articles

License

Articles in Journal of Chemistry, Environmental Sciences and its Applications (J. Chem. En. Sci. A.) by Chitkara University Publications are Open Access articles that are published with licensed under a Creative Commons Attribution- CC-BY 4.0 International License. Based on a work at https://jce.chitkara.edu.in. This license permits one to use, remix, tweak and reproduction in any medium, even commercially provided one give credit for the original creation.

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Creative Commons License Journal of Chemistry, Environmental Sciences and its Applications by Chitkara University Publications is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://jce.chitkara.edu.in
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